Williams, a rookie defensive lineman, was praised in camp but sustained a knee issue. His recovery pace will influence SF’s interior pressure plan and early-season depth, shaping both the defensive front and fantasy upside for IDP managers.

Williams was listed inactive due to a knee injury, depriving SF of an immediate edge presence. The slow start could push him into a bigger workload in Week 2 if the knee responds, but the absence also opens early opportunities for others to claim snaps and showcase depth at the position.

Williams stands out as an underrated 49ers rookie who could push for a depth-chart move after a knee tweak sidelined him in practice. His ability to translate college success to the pro level will determine early-season roles, and a standout performance in preseason could fast-track him into meaningful reps.

Mykel Williams, the rookie first-round pick, is dealing with a minor ankle injury, which has raised concerns about his early momentum at the NFL level.

Mykel Williams is leveraging the opportunity presented by Bosa's absence to secure a potentially significant role in the 49ers' defense, with the coaching staff closely monitoring his performance during practices.